Pharmacist Qualifying Examination[PEBC-Canada] MCQ Quiz Hub

1. Normal haemoglobin is made up of
2 alpha globin chains, 2 beta globin chains & 2 heme moieties
2 alpha globin chains, 2 beta globin chains & 4 heme moieties
2 alpha globin chains, 1 beta globin chain & 3 heme moieties
4 alpha globin chains & 4 heme moieties

2. The oxygen affinity of the Fe++ site in heme is increased by
acidosis
alkalosis
decreased NADH-metHb reductase activity
increased 2,3 bisphosphoglycerate

3. Haematopoietic stem cells give rise to all these excep
: dendritic cells
Kupffer cells
mast cells
fibroblasts

4. Haemolytic disease of the newborn
develops signs and symptoms after delivery
is most common in Asia
occurs in Rh D + infants of Rh D – mothers
occurs in Rh D - infants of Rh D + mothers

5. The normal liver does not synthesise this protein
alpha feto protein
fibrinogen
immunoglobulin
insulin-like growth factor

6. The intrinsic system of clotting factor activation requires
factor VIIa
HMW kininogen
tissue thromboplastin
von Willebrand factor

7. Plasmin
is inhibited by tissue factor pathway inhibitor
is not present in normal blood vessels
is secreted by activated plasma cells
lyses fibrin and fibrinogen

8. Lymphatic fluid
absorbs water-insoluble dietary fat
contains anticoagulant substances
does not normally contain white blood cells
has a higher protein content than plasma

9. Platelets have
a half life in the circulation of 4 days
an average size of 1/10th that of a RBC
blood group antigens on their cell membranes
small, dense nuclei

10. A haemolytic transfusion reaction will occur when
A blood is transfused into an AB patient
AB blood is transfused into an O patient
O positive blood is transfused into an O negative patient
O negative blood is transfused into an AB positive patient